Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9604228 | 0.77 | PTGER4 (0.58) | PTGER4BRD4KDM4EHDAC6SLC6A4 | |
| SCHEMBL22073753 | 0.68 | ALDH1A1 (0.38) | KDM4E | |
| SCHEMBL14838605 | 0.68 | RAPGEF4 (0.48) | PTGER4BRD4 | |
| SCHEMBL20194290 | 0.65 | HDAC1 (0.48) | PTGER4HDAC6 | |
| SCHEMBL24388002 | 0.65 | PTGER4 (0.49) | PTGER4BRD4KDM4EHDAC6SLC6A4 | |
| SCHEMBL424798 | 0.65 | TDP1 (0.56) | KDM4E | |
| SCHEMBL20194275 | 0.65 | PTGER4 (0.36) | PTGER4BRD4 | |
| SCHEMBL20194285 | 0.65 | PTGER4 (0.46) | PTGER4CREBBPHDAC6 | |
| SCHEMBL20194287 | 0.64 | HDAC1 (0.54) | PTGER4 | |
| SCHEMBL11365078 | 0.63 | TDP1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970139-B1 | HDAC INHIBITORS | BIOMARIN PHARM INC (US) | 2018-05-30 | — | — | EP | disclosed |