SCHEMBL424798

SCHEMBL424798

Cc1ccc(-c2ccc(-c3ccc(C)cc3N)cc2)c(N)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.56
CYP3A4 P08684 3/20 0.56
ALOX15 P16050 2/20 0.56
TP53 P04637 1/20 0.56
THRB P10828 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ALDH1A1 P00352 6/20 0.54
HSD17B10 Q99714 3/20 0.50
CA1 P00915 1/20 0.48
TSHR P16473 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOB P27338 2/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11365078 0.98 TDP1 (0.54) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL3791628 0.93 TDP1 (0.50) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL2971553 0.89 ALDH1A1 (0.54) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL6365723 0.87 TDP1 (0.65) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL30839750 0.87 TDP1 (0.65) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL30839742 0.87 TDP1 (0.65) TDP1CYP3A4ALOX15TP53THRB
Hydrochloric Acid SCHEMBL9310471 0.87 ALDH1A1 (0.52) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL2955919 0.86 CYP3A4 (0.50) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL14037036 0.86 TDP1 (0.44) TDP1CYP3A4ALOX15TP53THRB
SCHEMBL4477118 0.85 CYP46A1 (0.50) TDP1CYP3A4ALOX15TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8545988-B2 Polyetherimide and polyetherimide sulfone blends having automotive lighting applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-7928155-B2 Compositions and methods for polymer composites SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-04-19 US claimed
EP-2032611-A2 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 EP claimed
EP-1937774-A2 BLENDS OF POLY ARYL ETHER KETONES AND POLYETHERIMIDE SULFONES General Electric Company (US) 2008-07-02 EP claimed
WO-2008002891-A2 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 WO claimed
US-20070299189-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-12-27 US claimed
US-7253230-B2 Method of manufacture of polyester molding compositions and articles produced therefrom GENERAL ELECTRIC COMPANY (US) 2007-08-07 US claimed
WO-2007035402-A2 IMPROVED POLY ARYL ETHER KETONE POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-03-29 WO claimed
US-20070066765-A1 Polyarlyl ether ketone polymer blends GENERAL ELECTRIC COMPANY (US) 2007-03-22 US claimed
EP-4747299-A1 THERMALLY-CONDUCTING, ELECTRICALLY-INSULATING POLYIMIDE-POLYSILOXANE-BASED POLYMER COMPOSITE MATERIALS, TUBINGS MADE THEREFROM, AND SYSTEMS INCLUDING SUCH MATERIALS AND TUBINGS Parker-Hannifin Corporation (US) 2026-05-27 EP disclosed
US-12577468-B2 Thermoplastic compositions and uses thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-17 US disclosed
EP-4676734-A1 UNDERWATER PIPE COMPRISING AN INNER SEALING SHEATH MADE OF POLYARYLETHERKETONE TechnipFMC Subsea France (FR) 2026-01-14 EP disclosed
EP-4677028-A1 DUCTILE POLYARYLETHERKETONE COMPOSITIONS ARKEMA France (FR) 2026-01-14 EP disclosed
US-20250115717-A1 POLYETHERIMIDE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND INJECTION MOLDED ARTICLES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-04-10 US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-4826720-A Directly solderable three-dimensional electrically conductive circuit components and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-02 US disclosed
EP-0120183-B1 CONTINUOUS PROCESS FOR PREPARING POLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 1988-12-07 EP disclosed
US-4532054-A Including fluoropolymer, lubricant, reinforcing agent GENERAL ELECTRIC COMPANY (US) 1985-07-30 US disclosed
EP-0120130-A1 Polyetherimide bearing compositions GENERAL ELECTRIC COMPANY (US) 1984-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577468-B2 Thermoplastic compositions and uses thereof ALAD, ACMSD, DDC TDP1 1683/4885CYP3A4 292/4885ALOX15 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.