SCHEMBL2019443

SCHEMBL2019443

O=C1N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 10/20 0.73
HDAC1 Q13547 9/20 0.73
HDAC6 Q9UBN7 5/20 0.64
HDAC3 O15379 3/20 0.64
HDAC7 Q8WUI4 3/20 0.64
HDAC2 Q92769 3/20 0.64
HDAC10 Q969S8 3/20 0.64
HDAC11 Q96DB2 3/20 0.64
HDAC8 Q9BY41 3/20 0.64
HDAC9 Q9UKV0 3/20 0.64
HDAC5 Q9UQL6 3/20 0.64
SMN1; SMN2 Q16637 1/20 0.58
TRPM8 Q7Z2W7 1/20 0.56
F2 P00734 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173749 1.00 HDAC4 (0.73) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL18311480 1.00 HDAC4 (0.73) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL29355458 1.00 HDAC4 (0.73) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL6248993 1.00 HDAC4 (0.73) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL22286556 1.00 HDAC4 (0.73) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL25986065 0.96 HDAC4 (0.72) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL30540151 0.96 HDAC4 (0.72) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL24614335 0.92 HDAC4 (0.64) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL24614260 0.92 HDAC4 (0.64) HDAC4HDAC1HDAC6HDAC3HDAC7
SCHEMBL24614249 0.92 HDAC4 (0.64) HDAC4HDAC1HDAC6HDAC3HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE MICROBA IP PTY LTD (AU) 2026-01-29 US claimed
EP-4594325-A1 PEG-MODIFIED CYCLIC DIPEPTIDES Novmetapharma Co., Ltd. (KR) 2025-08-06 EP claimed
CN-119775430-A Mineral composite peptide and preparation and application thereof 中国科学院烟台海岸带研究所 2025-04-08 CN claimed
US-12186312-B2 Sleep improving agent Amino Up Co., Ltd. (JP) 2025-01-07 US claimed
CN-119072244-A Bacterial strains for the treatment of diseases 美克罗巴知识产权私人有限公司 2024-12-03 CN claimed
EP-4429482-A1 BACTERIAL STRAINS FOR TREATING DISEASE Microba IP Pty Limited (AU) 2024-09-18 EP claimed
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-05-02 US claimed
WO-2024069524-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-04-04 WO claimed
US-20230398158-A1 NEW COMPOSITION FOR TREATMENT OF SKIN CONDITIONS LACTOBIO A/S (DK) 2023-12-14 US claimed
EP-4240826-A1 NEW COMPOSITION FOR TREATMENT OF SKIN CONDITIONS Lactobio A/S (DK) 2023-09-13 EP claimed
WO-2023081980-A1 BACTERIAL STRAINS FOR TREATING DISEASE MICROBA IP PTY LTD (AU) 2023-05-19 WO claimed
US-20230017155-A1 SLEEP IMPROVING AGENT Amino Up Co., Ltd. (JP) 2023-01-19 US claimed
WO-2022096573-A9 NEW COMPOSITION FOR TREATMENT OF SKIN CONDITIONS LACTOBIO A/S (DK) 2022-10-27 WO claimed
US-11478473-B2 Sleep improving agent Amino Up Co., Ltd. (JP) 2022-10-25 US claimed
WO-2022096573-A1 NEW COMPOSITION FOR TREATMENT OF SKIN CONDITIONS LACTOBIO A/S (DK) 2022-05-12 WO claimed
CN-111378595-B Burkholderia agricultural biocontrol strain Ba1 and application thereof 中国林业科学研究院亚热带林业研究所 2021-04-27 CN claimed
EP-4720316-A2 NON-VIRAL CELL ENGINEERING Arsenal Biosciences, Inc. (US) 2026-04-08 EP disclosed
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE MICROBA IP PTY LTD (AU) 2026-01-29 US disclosed
US-20040024180-A1 Process for the production of 2,5 -diketopiperazines,2,5-diketopiperazines , dipeptides and their use thereof DEGUSSA AG (DE) 2004-02-05 US disclosed
EP-1386543-A1 New bacterial strain and the use thereof Medipharm AB (SE) 2004-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES LNPEP, ANPEP, DNPEP HDAC4 1691/4885HDAC1 506/4885HDAC6 1697/4885
US-11478473-B2 Sleep improving agent HSF1, HSPH1, HSPA2 HDAC4 126/4885HDAC1 254/4885HDAC6 208/4885
US-20230017155-A1 SLEEP IMPROVING AGENT HSF1, HSPH1, HSPA2 HDAC4 127/4885HDAC1 227/4885HDAC6 279/4885
US-12186312-B2 Sleep improving agent HSF1, HSPH1, HSPA2 HDAC4 127/4885HDAC1 227/4885HDAC6 279/4885
US-20040024180-A1 Process for the production of 2,5 -diketopiperazines,2,5-diketopiperazines , dipeptides and their use thereof DHPS, DPP7, VIP HDAC4 3488/4885HDAC1 3638/4885HDAC6 2121/4885
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE VIP, SI, ALPI HDAC4 3455/4885HDAC1 3093/4885HDAC6 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.