Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663343 | 0.92 | SIGMAR1 (0.35) | KEAP1SMN1; SMN2S1PR1S1PR3S1PR5 | |
| SCHEMBL7215578 | 0.87 | — | — | |
| SCHEMBL17143175 | 0.81 | ALOX15 (0.33) | SMN1; SMN2 | |
| SCHEMBL1360772 | 0.81 | OPRD1 (0.36) | ADRA1DADRA1AADRA1BS1PR1S1PR3 | |
| SCHEMBL1360771 | 0.79 | S1PR1 (0.34) | ADRA1DADRA1AADRA1BS1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL27833501 | 0.79 | KDM4E (0.33) | SMN1; SMN2 | |
| SCHEMBL28123990 | 0.79 | GBA2 (0.47) | S1PR1S1PR3S1PR5S1PR4GBA2 | |
| SCHEMBL2785862 | 0.78 | — | — | |
| SCHEMBL3265496 | 0.78 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4GBA2 | |
| SCHEMBL2902792 | 0.77 | KEAP1 (0.34) | KEAP1SMN1; SMN2DPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268008-B1 | COMPOUNDS THAT ARE ANALOGS OF SQUALAMINE, USED AS ANTIBACTERIAL AGENTS | VIRBAC (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3327017-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Merck Patent GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |