Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982792 | 0.81 | RXRA (0.53) | RXRARXRBCNR2KMOCYP3A4 | |
| SCHEMBL8438374 | 0.81 | ATM (0.77) | ATMTDP1L3MBTL1CNR2KMO | |
| SCHEMBL11183749 | 0.79 | ATM (0.74) | ATMTDP1L3MBTL1CNR2KMO | |
| SCHEMBL3364840 | 0.78 | RXRA (0.51) | RXRARXRBKMOSRD5A2HPGD | |
| SCHEMBL548283 | 0.78 | L3MBTL1 (0.61) | ATMTDP1L3MBTL1SRD5A2PBRM1 | |
| SCHEMBL16858233 | 0.77 | KMO (0.72) | RXRARXRBATMTDP1L3MBTL1 | |
| SCHEMBL3684740 | 0.76 | ATM (0.63) | RXRARXRBATMTDP1L3MBTL1 | |
| SCHEMBL12551733 | 0.76 | ATM (0.68) | RXRARXRBATMTDP1L3MBTL1 | |
| SCHEMBL7325996 | 0.76 | L3MBTL1 (0.57) | ATMTDP1L3MBTL1SRD5A2PBRM1 | |
| SCHEMBL11432364 | 0.75 | KMT2A (0.46) | MEN1KMT2AALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081682-B1 | LITHIUM REAGENT POROUS METAL OXIDE COMPOSITIONS | SIGNA CHEMISTRY INC (US) | 2018-05-30 | — | — | EP | disclosed |