Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183592 | 0.78 | HTR6 (0.39) | HTR6KDM4ELMNAPOLBHTR1A | |
| SCHEMBL21474013 | 0.74 | HPGD (0.47) | HTR6KDM4EHPGDHSD17B10 | |
| SCHEMBL20183533 | 0.71 | KDM4E (0.43) | HTR6KDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL20195133 | 0.71 | PTGER4 (0.44) | HTR6SLC6A4 | |
| SCHEMBL20183527 | 0.71 | CNR2 (0.43) | HTR6SMN1; SMN2LMNA | |
| SCHEMBL20195236 | 0.69 | METAP2 (0.36) | KDM4EHPGDSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL20183657 | 0.67 | PDE4A (0.45) | HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL28325696 | 0.64 | GRM2 (0.38) | HTR6KDM4E | |
| SCHEMBL28325700 | 0.62 | KDM4E (0.42) | KDM4EHPGDSMN1; SMN2LMNAPOLB | |
| Hydrochloric Acid SCHEMBL1148906 | 0.61 | QDPR (0.65) | HTR6KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |