Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.41 |
| ▸ | DRD3 | P35462 | 10/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18581653 | 1.00 | DRD2 (0.41) | DRD2DRD3ALOX5NOTUMENPP2 | |
| SCHEMBL5246364 | 0.83 | DRD2 (0.51) | DRD2DRD3NOTUM | |
| SCHEMBL21670319 | 0.78 | HRH3 (0.41) | — | |
| SCHEMBL1847671 | 0.75 | ALDH1A1 (0.41) | DRD2ALOX5TSHR | |
| SCHEMBL20195364 | 0.73 | KCNH2 (0.35) | CYP2D6TSHR | |
| SCHEMBL20048771 | 0.72 | ENPP2 (0.41) | DRD2DRD3NOTUMENPP2TSHR | |
| SCHEMBL17970229 | 0.72 | ENPP2 (0.41) | DRD2DRD3NOTUMENPP2TSHR | |
| SCHEMBL20691429 | 0.72 | ENPP2 (0.41) | DRD2DRD3NOTUMENPP2TSHR | |
| SCHEMBL18331769 | 0.72 | ENPP2 (0.41) | DRD2DRD3NOTUMENPP2TSHR | |
| SCHEMBL18724638 | 0.72 | ENPP2 (0.41) | DRD2DRD3NOTUMENPP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327021-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | Yangji Chemical Co., Ltd. (KR) | 2018-05-30 | — | — | EP | disclosed |