Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22038784 | 0.90 | HTR7 (0.41) | SMN1; SMN2NR1H4NPSR1 | |
| SCHEMBL20844967 | 0.82 | NR1H4 (0.35) | SMN1; SMN2NR1H4MAPTMAPK1 | |
| SCHEMBL22038791 | 0.81 | HTR7 (0.41) | MAPTMAPK1 | |
| SCHEMBL20195405 | 0.78 | NPSR1 (0.34) | NPSR1 | |
| SCHEMBL22037708 | 0.78 | HTR7 (0.42) | NR1H4MAPT | |
| SCHEMBL22037218 | 0.77 | CYP3A4 (0.35) | SMN1; SMN2NR1H4MAPK1 | |
| SCHEMBL22037209 | 0.77 | NR1H4 (0.32) | NR1H4RXRARXRBRXRG | |
| SCHEMBL22037272 | 0.77 | HTR7 (0.41) | — | |
| SCHEMBL18831732 | 0.77 | HTT (0.39) | SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL18831547 | 0.76 | MAOA (0.37) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |