SCHEMBL20195405

SCHEMBL20195405

Cc1ccc(C)c(OCc2c(Cl)cccc2N(N)C(=O)N(C)N)n1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.34
BDKRB2 P30411 10/20 0.33
CYP3A4 P08684 2/20 0.33
CD38 P28907 2/20 0.33
PPARG P37231 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195558 0.84 SSTR4 (0.37) PPARG
SCHEMBL18831638 0.80 MRGPRX4 (0.39)
SCHEMBL20195396 0.78 SMN1; SMN2 (0.38) NPSR1
SCHEMBL22038784 0.77 HTR7 (0.41) NPSR1
SCHEMBL20195581 0.76 KMT2A (0.38) NPSR1
SCHEMBL20195623 0.76 MCL1 (0.42) BDKRB2CYP3A4CD38PPARG
SCHEMBL20195479 0.76 KMT2A (0.38) NPSR1BDKRB2CYP3A4CD38NPC1
SCHEMBL23506114 0.76 GALR3 (0.36)
SCHEMBL20195594 0.75 BDKRB2 (0.43) BDKRB2RAB9A
SCHEMBL18831573 0.74 MET (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed