Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195402 | 0.85 | GABRA5 (0.39) | L3MBTL1NPC1RAB9AGABRA5MAPK1 | |
| SCHEMBL20195561 | 0.85 | GABRA5 (0.39) | RXFP1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL20195455 | 0.85 | NPC1 (0.38) | NPC1RAB9AGABRA5ALDH1A1GRM5 | |
| SCHEMBL20195459 | 0.84 | ADORA2A (0.38) | KMT2AL3MBTL1NPC1RAB9AGABRA5 | |
| SCHEMBL18831576 | 0.79 | GLA (0.37) | KMT2AL3MBTL1RAB9AGLAMEN1 | |
| SCHEMBL20686599 | 0.79 | GLA (0.37) | KMT2AL3MBTL1RAB9AGLAMEN1 | |
| SCHEMBL22590951 | 0.79 | GLA (0.37) | KMT2AL3MBTL1RAB9AGLAMEN1 | |
| SCHEMBL22563751 | 0.78 | KDM4E (0.34) | RXFP1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL18831446 | 0.77 | KMT2A (0.36) | KMT2AL3MBTL1NPC1RAB9AMAPK1 | |
| SCHEMBL18831766 | 0.76 | MAPT (0.37) | L3MBTL1NPC1RAB9AMAPTMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |