SCHEMBL22563751

SCHEMBL22563751

CCOc1cccc(N(N)C(=O)N(C)N)c1COc1ccn(-c2ccc(F)cc2)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
KMT2A Q03164 3/20 0.32
RXFP1 Q9HBX9 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
UBE2N P61088 2/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
AGTR1 P30556 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563863 0.90 KDM4E (0.35) KDM4EL3MBTL1NPC1LMNARAB9A
SCHEMBL22563952 0.85 MGLL (0.33) KDM4EL3MBTL1NR1H4KMT2AFAAH
SCHEMBL20845268 0.84 L3MBTL1 (0.37) KDM4EL3MBTL1NPC1LMNAMAPT
SCHEMBL22563756 0.84 DGAT1 (0.34) L3MBTL1NPC1LMNAMAPTRAB9A
SCHEMBL19909875 0.81 NR1H4 (0.37) KDM4ENPC1LMNARAB9ANR1H4
SCHEMBL22564019 0.81 NR1H4 (0.33) MAPTNR1H4
SCHEMBL22563891 0.81 NR1H4 (0.37) KDM4EL3MBTL1LMNAMAPTNR1H4
SCHEMBL22564003 0.80 ALDH1A1 (0.39) KDM4EL3MBTL1NPC1LMNAMAPT
SCHEMBL22563938 0.80 NR1H4 (0.35) KDM4ENPC1RAB9ANR1H4KMT2A
SCHEMBL22564358 0.80 NPSR1 (0.34) KDM4ENPC1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed