Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.32 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195402 | 0.87 | GABRA5 (0.39) | GABRA5TSHRGRM5ALDH1A1L3MBTL1 | |
| SCHEMBL20195398 | 0.84 | RXFP1 (0.36) | ADORA2AGABRA5GRM5ALDH1A1KMT2A | |
| SCHEMBL20195455 | 0.84 | NPC1 (0.38) | GABRA5TSHRGRM5ALDH1A1NPC1 | |
| SCHEMBL22037265 | 0.84 | FFAR4 (0.35) | GABRA5KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL20195604 | 0.84 | GABRA5 (0.38) | GABRA5ALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL20845040 | 0.81 | SLC16A3 (0.32) | TDP1ALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL20195410 | 0.78 | SGMS2 (0.42) | TSHRTDP1ALDH1A1KMT2AATM | |
| SCHEMBL18831653 | 0.77 | MRGPRX4 (0.40) | GRM5RAB9AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL16446199 | 0.75 | GABRA5 (0.47) | ADORA2AGABRA5GRM5ALDH1A1NPC1 | |
| SCHEMBL22590911 | 0.75 | ALDH1A1 (0.33) | TDP1ALDH1A1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |