Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195599 | 0.83 | GABRA5 (0.43) | GABRA5HCRTR2NR1H4HCRTR1 | |
| SCHEMBL18503932 | 0.80 | PDE4D (0.36) | ASPHKDM8ALOX5APFEN1NR1H4 | |
| SCHEMBL22563821 | 0.79 | PDE4D (0.35) | ASPHKDM8ALOX5APFEN1NR1H4 | |
| SCHEMBL16385608 | 0.78 | RXRA (0.48) | PTGDR2KDM4EHRH2MEN1KMT2A | |
| SCHEMBL20195529 | 0.77 | HTT (0.46) | GABRA5MEN1KMT2A | |
| SCHEMBL20195565 | 0.77 | ALDH1A1 (0.44) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20195609 | 0.76 | MEN1 (0.51) | GABRA5L3MBTL1MEN1KMT2AHCRTR1 | |
| SCHEMBL3978369 | 0.74 | KDM4E (0.43) | ASPHKDM8KDM4ETDP1L3MBTL1 | |
| SCHEMBL20195588 | 0.74 | HTR1A (0.38) | GABRA5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL17788221 | 0.74 | SLC22A12 (0.43) | NR1H4KDM4ESTING1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |