Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195414 | 0.83 | TDP1 (0.41) | L3MBTL1CHRNB2CHRNA4NPC1MAPT | |
| SCHEMBL20195514 | 0.79 | HTR1A (0.39) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18871645 | 0.75 | MAPT (0.33) | L3MBTL1BDKRB2MAPTSLC6A2SLC6A4 | |
| SCHEMBL18871226 | 0.74 | MAPT (0.35) | L3MBTL1NPC1MAPTRAB9ASLC6A2 | |
| SCHEMBL18870767 | 0.73 | SLC22A12 (0.32) | L3MBTL1NPC1MAPTRAB9ASLC6A2 | |
| SCHEMBL20686619 | 0.73 | MRGPRX4 (0.42) | MAPTSLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL22563873 | 0.70 | SIGMAR1 (0.39) | — | |
| SCHEMBL20195533 | 0.70 | P2RX7 (0.38) | L3MBTL1CASP6NPC1MAPTRAB9A | |
| SCHEMBL18871256 | 0.70 | PTGDR2 (0.35) | — | |
| SCHEMBL27736337 | 0.69 | SMN1; SMN2 (0.38) | CASP6NPC1MAPTRAB9ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |