Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195473 | 0.83 | L3MBTL1 (0.33) | TDP1SGMS2KDM4EMAPTL3MBTL1 | |
| SCHEMBL20195514 | 0.81 | HTR1A (0.39) | LMNATSHRHSD17B10CHRNB2CHRNA4 | |
| SCHEMBL20686856 | 0.77 | SMN1; SMN2 (0.40) | TP53MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL20195620 | 0.74 | KMT2A (0.32) | KMT2AMEN1KDM4EALDH1A1ATM | |
| SCHEMBL18831566 | 0.72 | MRGPRX4 (0.37) | SMN1; SMN2 | |
| SCHEMBL20195450 | 0.72 | HDAC1 (0.38) | — | |
| SCHEMBL20686678 | 0.72 | PTGER1 (0.36) | LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27736337 | 0.71 | SMN1; SMN2 (0.38) | TDP1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL20686842 | 0.70 | ADRA2A (0.33) | LMNASMN1; SMN2RAB9A | |
| SCHEMBL18831561 | 0.70 | MRGPRX4 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |