Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195478 | 0.84 | GABRA5 (0.38) | GABRA5GRM5GRM1HSD17B3 | |
| SCHEMBL20195540 | 0.79 | SGMS2 (0.34) | — | |
| SCHEMBL18871326 | 0.78 | MRGPRX4 (0.34) | — | |
| SCHEMBL18871659 | 0.78 | MRGPRX4 (0.32) | — | |
| SCHEMBL20195396 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL22037708 | 0.75 | HTR7 (0.42) | — | |
| SCHEMBL22038784 | 0.74 | HTR7 (0.41) | — | |
| SCHEMBL20195402 | 0.73 | GABRA5 (0.39) | GABRA5GRM5 | |
| SCHEMBL22037209 | 0.72 | NR1H4 (0.32) | GRM5 | |
| SCHEMBL22037272 | 0.72 | HTR7 (0.41) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |