Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 8/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195459 | 0.84 | ADORA2A (0.38) | GABRA5HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL14150253 | 0.77 | GABRA5 (0.49) | GABRA5HCRTR2PTGER1KDM4EHCRTR1 | |
| SCHEMBL22037265 | 0.77 | FFAR4 (0.35) | GABRA5KDM4E | |
| SCHEMBL20686703 | 0.75 | ALDH1A1 (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL20195410 | 0.75 | SGMS2 (0.42) | ALDH1A1GAANPSR1 | |
| SCHEMBL18831653 | 0.75 | MRGPRX4 (0.40) | PTGER1NPSR1 | |
| SCHEMBL20845040 | 0.74 | SLC16A3 (0.32) | PTGER1ALDH1A1 | |
| SCHEMBL22037270 | 0.74 | PTGER1 (0.43) | PTGER1 | |
| SCHEMBL21317987 | 0.73 | PTGER1 (0.41) | PTGER1KDM4E | |
| SCHEMBL22590911 | 0.72 | ALDH1A1 (0.33) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |