Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195587 | 0.87 | P2RX7 (0.43) | SGMS2P2RX7AKR1C3KMT2ATP53 | |
| SCHEMBL20195641 | 0.86 | P2RX7 (0.43) | SGMS2P2RX7KMT2AALDH1A1ATM | |
| SCHEMBL20195631 | 0.82 | SSTR4 (0.41) | SGMS2P2RX7KMT2ACYP1A2CYP2C19 | |
| SCHEMBL20195627 | 0.82 | ALDH1A1 (0.48) | SGMS2TDP1P2RX7KMT2AALDH1A1 | |
| SCHEMBL17788257 | 0.79 | SLC22A12 (0.41) | SGMS2AKR1C3ALDH1A1POLBNPSR1 | |
| SCHEMBL17788244 | 0.79 | RAB9A (0.42) | SGMS2AKR1C3NPSR1TP53HTT | |
| SCHEMBL27478031 | 0.77 | MRGPRX4 (0.45) | TDP1KMT2AALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL16385606 | 0.77 | PTGDR2 (0.50) | SGMS2AKR1C3 | |
| SCHEMBL17788240 | 0.77 | MRGPRX4 (0.50) | KMT2AL3MBTL1POLBTP53 | |
| SCHEMBL20195560 | 0.76 | ALDH1A1 (0.50) | TDP1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |