Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195628 | 0.85 | TP53 (0.44) | MRGPRX4PPARGLMNAALDH1A1APEX1 | |
| SCHEMBL20195623 | 0.85 | MCL1 (0.42) | CLCN2MRGPRX4PPARGMCL1BAK1 | |
| SCHEMBL20195619 | 0.84 | KMT2A (0.41) | POLBPPARGALDH1A1APEX1KDM4E | |
| SCHEMBL16385271 | 0.76 | RXRA (0.52) | CLCN2MRGPRX4PTGDR2ALDH1A1APEX1 | |
| SCHEMBL18831634 | 0.76 | MRGPRX4 (0.53) | CLCN2MRGPRX4APEX1 | |
| SCHEMBL16920923 | 0.75 | MRGPRX4 (0.49) | MRGPRX4ALDH1A1APEX1KDM4EHPGD | |
| SCHEMBL20195479 | 0.75 | KMT2A (0.38) | POLBMCL1BAK1CD38ALDH1A1 | |
| SCHEMBL16920918 | 0.73 | MRGPRX4 (0.56) | MRGPRX4HSD17B10 | |
| SCHEMBL578127 | 0.72 | CLCN2 (0.56) | CLCN2MRGPRX4ALDH1A1KDM4EHPGD | |
| SCHEMBL18831439 | 0.72 | MRGPRX4 (0.47) | MRGPRX4ALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |