Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195619 | 0.89 | KMT2A (0.41) | MEN1HTTKMT2AAPEX1KDM4E | |
| SCHEMBL20195659 | 0.85 | CLCN2 (0.40) | APEX1KDM4ELMNAMRGPRX4HSD17B10 | |
| SCHEMBL20195598 | 0.84 | KMT2A (0.49) | MEN1HTTKMT2AAPEX1L3MBTL1 | |
| SCHEMBL20195590 | 0.83 | GABRA5 (0.44) | TP53MEN1HTTKMT2AAPEX1 | |
| SCHEMBL20195623 | 0.83 | MCL1 (0.42) | TP53MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL20195589 | 0.83 | ALDH1A1 (0.44) | TP53MEN1HTTKMT2AKDM4E | |
| SCHEMBL18831787 | 0.78 | MRGPRX4 (0.46) | APEX1LMNAMRGPRX4SMN1; SMN2NPC1 | |
| SCHEMBL20195612 | 0.77 | GRM5 (0.36) | TP53MEN1HTTKMT2AKDM4E | |
| SCHEMBL16920926 | 0.76 | MRGPRX4 (0.55) | APEX1L3MBTL1LMNAMRGPRX4SMN1; SMN2 | |
| SCHEMBL1989711 | 0.74 | L3MBTL1 (0.50) | MEN1HTTKMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |