Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195479 | 0.90 | KMT2A (0.38) | MCL1BAK1TP53ALDH1A1KMT2A | |
| SCHEMBL20195659 | 0.85 | CLCN2 (0.40) | MCL1BAK1CLCN2MRGPRX4SORT1 | |
| SCHEMBL20195619 | 0.84 | KMT2A (0.41) | HTTALDH1A1KMT2APPARGMEN1 | |
| SCHEMBL20195628 | 0.83 | TP53 (0.44) | TP53HTTMRGPRX4TSHRALDH1A1 | |
| SCHEMBL20195622 | 0.82 | GABRA5 (0.46) | TP53HTTMRGPRX4TSHRSORT1 | |
| SCHEMBL20195405 | 0.76 | NPSR1 (0.34) | PPARGBDKRB2CYP3A4CD38 | |
| SCHEMBL18831597 | 0.76 | MRGPRX4 (0.50) | MCL1TP53HTTMRGPRX4 | |
| SCHEMBL16920930 | 0.75 | MRGPRX4 (0.49) | MCL1TP53HTTMRGPRX4KMT2A | |
| SCHEMBL20195639 | 0.74 | BDKRB2 (0.42) | BDKRB2CYP3A4 | |
| SCHEMBL20195657 | 0.74 | P2RX7 (0.36) | SORT1DHODHTTRCYP3A4CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |