Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.33 |
| ▸ | ATP4B | P51164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548466 | 0.84 | SREBF2 (0.35) | ATP4AATP4BLMNAMAPTRXFP1 | |
| SCHEMBL16535583 | 0.82 | SREBF2 (0.36) | ATP4AATP4BLMNAMAPTRXFP1 | |
| SCHEMBL20197304 | 0.80 | CDK2 (0.39) | MAPT | |
| SCHEMBL20197238 | 0.76 | CYP19A1 (0.44) | — | |
| SCHEMBL20197223 | 0.74 | SREBF2 (0.42) | LMNAMAPT | |
| SCHEMBL20197301 | 0.73 | KDM4E (0.34) | LMNAMAPT | |
| SCHEMBL20197235 | 0.73 | SREBF2 (0.42) | LMNAMAPT | |
| SCHEMBL20197159 | 0.73 | CYP19A1 (0.33) | — | |
| SCHEMBL20197337 | 0.71 | CYP1A2 (0.40) | MAPT | |
| SCHEMBL20197443 | 0.71 | C1S (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |