Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415622 | 0.77 | CALM1 (0.50) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL27895642 | 0.77 | KDM4E (0.42) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL20197185 | 0.77 | CCNC (0.43) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL10383867 | 0.77 | ALDH1A1 (0.47) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL5115091 | 0.77 | RECQL (0.50) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL28232093 | 0.77 | L3MBTL1 (0.53) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL8672787 | 0.77 | HTR2B (0.41) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL13562418 | 0.77 | NOS2 (0.53) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL30368122 | 0.77 | ALDH1A1 (0.47) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL23036046 | 0.74 | MAOB (0.46) | HTR2BCALM1L3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |