Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.45 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.45 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | BMP4 | P12644 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21868503 | 0.86 | ALDH1A1 (0.41) | KITGPR6PDE2ARORC | |
| SCHEMBL15264672 | 0.85 | ALDH1A1 (0.47) | KITGPR6RORC | |
| SCHEMBL15264465 | 0.81 | GPR6 (0.38) | KITGPR6PDE2ARORC | |
| SCHEMBL21779746 | 0.79 | CHKA (0.48) | KITCHKA | |
| SCHEMBL20411307 | 0.79 | MGLL (0.38) | KITGPR6PDE2ARORC | |
| SCHEMBL15266644 | 0.79 | CHRM1 (0.47) | — | |
| SCHEMBL30074248 | 0.78 | MGLL (0.55) | — | |
| SCHEMBL15267044 | 0.78 | ALDH1A1 (0.45) | KIT | |
| SCHEMBL15094923 | 0.78 | MGLL (0.55) | — | |
| SCHEMBL18713008 | 0.78 | LOXL2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |