SCHEMBL30074248

SCHEMBL30074248

Cc1cnccc1-c1ccc(CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 20/20 0.55
▸ PLA2G7 Q13093 3/20 0.49
▸ ABHD6 Q9BV23 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15094923 1.00 MGLL (0.55) MGLLPLA2G7ABHD6
SCHEMBL15101011 0.93 MGLL (0.59) MGLLPLA2G7ABHD6
SCHEMBL15094557 0.85 MGLL (0.57) MGLLPLA2G7ABHD6
SCHEMBL15264672 0.84 ALDH1A1 (0.47) MGLL
SCHEMBL20411307 0.83 MGLL (0.38) MGLL
SCHEMBL15100863 0.83 MGLL (0.55) MGLLPLA2G7ABHD6
SCHEMBL30074247 0.82 MGLL (0.55) MGLLPLA2G7ABHD6
SCHEMBL15094494 0.82 MGLL (0.55) MGLLPLA2G7ABHD6
SCHEMBL15267044 0.82 ALDH1A1 (0.45) MGLL
SCHEMBL15100905 0.80 MGLL (0.59) MGLLPLA2G7ABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018004-B2 Carbamate compounds and methods of making and using same H. LUNDBECK A/S (DK) 2024-06-25 — — US disclosed
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2024-02-22 — — US disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 — — US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 — — US disclosed
EP-4218785-A2 MITOCHONDRIA-TARGETING PEPTIDES Stealth BioTherapeutics Inc. (US) 2023-08-02 — — EP disclosed
EP-3723783-B1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC (US) 2023-02-15 — — EP disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530189-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 MGLL 54/4885PLA2G7 195/4885ABHD6 1/4885
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 MGLL 54/4885PLA2G7 195/4885ABHD6 1/4885
US-11795196-B2 Mitochondria-targeting peptides HSPE1, TFAM, TNNI3 MGLL 2728/4885PLA2G7 1440/4885ABHD6 3173/4885
US-12018004-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 MGLL 54/4885PLA2G7 195/4885ABHD6 1/4885
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 MGLL 2728/4885PLA2G7 1440/4885ABHD6 3173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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