Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15272578 | 0.80 | MRGPRX4 (0.38) | MRGPRX4 | |
| SCHEMBL2913539 | 0.76 | MRGPRX4 (0.32) | MRGPRX4 | |
| SCHEMBL1760358 | 0.76 | HCAR2 (0.41) | MRGPRX4 | |
| SCHEMBL830961 | 0.75 | NOS3 (0.36) | — | |
| SCHEMBL7573577 | 0.74 | ADORA3 (0.42) | MRGPRX4 | |
| SCHEMBL13771995 | 0.74 | BAZ2B (0.42) | MRGPRX4 | |
| SCHEMBL19836670 | 0.72 | KCNH2 (0.38) | — | |
| SCHEMBL24993307 | 0.72 | P2RX7 (0.42) | MRGPRX4 | |
| SCHEMBL14872363 | 0.72 | MRGPRX4 (0.57) | MRGPRX4 | |
| SCHEMBL22409169 | 0.71 | CDK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033336-B1 | INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2018-05-30 | — | — | EP | disclosed |