Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334320 | 0.83 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL2020026 | 0.74 | TDP1 (0.33) | MEN1KMT2ALMNAMAPTTDP1 | |
| SCHEMBL30530488 | 0.74 | CYSLTR1 (0.57) | MEN1KMT2ALMNARAB9AKDM4E | |
| SCHEMBL919524 | 0.74 | CYSLTR1 (0.57) | MEN1KMT2ALMNARAB9AKDM4E | |
| SCHEMBL919522 | 0.74 | CYSLTR1 (0.57) | MEN1KMT2ALMNARAB9AKDM4E | |
| SCHEMBL7249222 | 0.73 | PTGER1 (0.59) | MEN1KMT2ACYSLTR1CYSLTR2ABCC1 | |
| SCHEMBL7249226 | 0.73 | PTGER1 (0.59) | MEN1KMT2ACYSLTR1CYSLTR2ABCC1 | |
| SCHEMBL11833882 | 0.73 | RAB9A (0.55) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL10767985 | 0.72 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL29517086 | 0.72 | MEN1 (0.48) | MEN1KMT2ALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001374-A3 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2011-06-30 | — | — | WO | disclosed |