Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020024 | 0.74 | MEN1 (0.45) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8604002 | 0.72 | CNR2 (0.38) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL4961177 | 0.72 | ALDH1A1 (0.46) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9335553 | 0.72 | UNG (0.41) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL5810767 | 0.68 | MEN1 (0.34) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL3228023 | 0.66 | CNR2 (0.43) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL18463776 | 0.66 | NR4A2 (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9757049 | 0.66 | NR4A2 (0.41) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL9335423 | 0.65 | PRSS1 (0.38) | MAPTSMN1; SMN2NPC1ARCNR2 | |
| SCHEMBL4957637 | 0.65 | MAPT (0.44) | ALDH1A1MAPTMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001374-A3 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2011-06-30 | — | — | WO | disclosed |