Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634104 | 0.93 | XDH (0.40) | HSD17B10RXRAERN1CA1CA2 | |
| SCHEMBL25634115 | 0.88 | RARB (0.43) | HSD17B10RXRAERN1CA1CA2 | |
| SCHEMBL18504207 | 0.88 | HSD17B10 (0.49) | HSD17B10RXRAERN1CA1CA2 | |
| SCHEMBL29434900 | 0.84 | TP53 (0.50) | HSD17B10RXRACA1CA2MAP4K4 | |
| SCHEMBL15521776 | 0.84 | TP53 (0.50) | HSD17B10RXRACA1CA2MAP4K4 | |
| SCHEMBL29434901 | 0.84 | TP53 (0.50) | HSD17B10RXRACA1CA2MAP4K4 | |
| SCHEMBL14768869 | 0.82 | ALDH1A1 (0.50) | HSD17B10RXRACA1CA2MAP4K4 | |
| SCHEMBL12780511 | 0.82 | HSD17B10 (0.56) | HSD17B10RXRAERN1CA1CA2 | |
| SCHEMBL12312924 | 0.81 | HCRTR1 (0.46) | MAP4K4PTPN11HCRTR1HCRTR2SRD5A2 | |
| SCHEMBL12535966 | 0.81 | RXRA (0.54) | HSD17B10RXRAERN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147284-A1 | Amorphous Metal-Organic Frameworks | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147284-A1 | Amorphous Metal-Organic Frameworks | ZKSCAN2, IKZF3, SLC30A6 | HSD17B10 4490/4885RXRA 384/4885ERN1 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.