Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312930 | 0.92 | HCRTR1 (0.45) | ALDH1A1SMN1; SMN2MAP4K4RXRARXRB | |
| SCHEMBL18504207 | 0.91 | HSD17B10 (0.49) | MAP4K4RXRARXRBHSD17B10CA1 | |
| SCHEMBL15132369 | 0.90 | RXRA (0.56) | ALDH1A1SMN1; SMN2MAP4K4RXRARXRB | |
| SCHEMBL16769650 | 0.87 | RARB (0.50) | ALDH1A1SMN1; SMN2MAP4K4RXRARXRB | |
| SCHEMBL16769640 | 0.84 | RXRA (0.49) | MAP4K4RXRARXRBHSD17B10CA1 | |
| SCHEMBL12312924 | 0.84 | HCRTR1 (0.46) | ALDH1A1MAP4K4SRD5A2HCRTR1HCRTR2 | |
| SCHEMBL19627078 | 0.84 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAP4K4RXRARXRB | |
| SCHEMBL16769663 | 0.82 | HSD17B10 (0.44) | ALDH1A1SMN1; SMN2RXRARXRBSRD5A2 | |
| SCHEMBL20201334 | 0.82 | HSD17B10 (0.41) | ALDH1A1MAP4K4RXRARXRBSRD5A2 | |
| SCHEMBL12780511 | 0.82 | HSD17B10 (0.56) | ALDH1A1RXRARXRBSRD5A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593132-B2 | Metal-organic frameworks (MOF) for gas capture | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-02-19 | — | — | US | disclosed |
| US-8470075-B2 | Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration | NORTHWESTERN UNIVERSITY (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130061752-A1 | Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration | NORTHWESTERN UNIVERSITY (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130061752-A1 | Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration | TPR, FABP7, PAICS | ALDH1A1 2767/4885SMN1; SMN2 2958/4885MAP4K4 3439/4885 |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | HAO2, TRPM6, FTH1 | ALDH1A1 806/4885SMN1; SMN2 3126/4885MAP4K4 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.