SCHEMBL2020142

SCHEMBL2020142

C=C(C)COc1ccccc1.[Na]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.60
ALOX15 P16050 1/20 0.54
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
KCNA3 P22001 1/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
KAT6A Q92794 1/20 0.44
MAPT P10636 1/20 0.43
ALOX12 P18054 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
ALPL P05186 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486040 0.98 GPR174 (0.62) GPR174ALOX15LMNAALDH1A1RECQL
SCHEMBL7438279 0.90 GPR174 (0.59) GPR174ALOX15SMN1; SMN2RAB9AMAOB
SCHEMBL10338925 0.86 GPR174 (0.58) GPR174ALOX15LMNAALDH1A1SMN1; SMN2
SCHEMBL2429681 0.86 GPR174 (0.59) GPR174ALOX15LMNAALDH1A1SMN1; SMN2
SCHEMBL97376 0.84 ALOX15 (0.60) ALOX15LMNAALDH1A1RECQLSMN1; SMN2
SCHEMBL7141666 0.83 GPR174 (0.56) GPR174LMNAMAOB
SCHEMBL1229367 0.83 PTGS1 (0.61) GPR174LMNASMN1; SMN2MEN1KMT2A
SCHEMBL9622079 0.83 LMNA (0.52) GPR174ALOX15LMNAALDH1A1SMN1; SMN2
SCHEMBL15761342 0.82 GPR174 (0.52) GPR174ALOX15LMNAALDH1A1SMN1; SMN2
SCHEMBL14690425 0.81 GPR174 (0.55) GPR174ALOX15LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3302586-A1 ARTICLE OF COMMERCE CONTAINING ABSORBENT ARTICLE The Procter and Gamble Company (US) 2018-04-11 EP disclosed
EP-2657329-B1 Sequestering agent used in detergents with high calcium binding capacity VIKING TEMIZLIK VE KOZMETIK ÜRÜNLERI PAZARLAMA SANAYI TICARET ANOMIM SIRKETI (TR) 2017-10-18 EP disclosed
WO-2016200716-A1 ARTICLE OF COMMERCE CONTAINING ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2016-12-15 WO disclosed
EP-2657329-A1 Sequestering agent used in detergents with high calcium binding capacity Viking Temizlik Ve Kozmetik Ürünleri Pazarlama Sanayi Ticaret Anomim Sirketi (TR) 2013-10-30 EP disclosed
US-7964686-B2 Aqueous treatment composition for use as anti-scalant and dispersantThe composition includes a polymer containing low amounts of sulfonate that prove as effective in carbonate and phosphate inhibition as polymers containing much higher amounts of sulfonate. AKZO NOBEL N.V. (NL) 2011-06-21 US disclosed
EP-1725643-B1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS PROCTER & GAMBLE (US) 2008-07-02 EP disclosed
EP-1725642-B1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS PROCTER & GAMBLE (US) 2008-05-14 EP disclosed
US-20070185295-A1 Aqueous treatment compositions and polymers for use therein AKZO NOBEL N.V. (NL) 2007-08-09 US disclosed
EP-1725643-A1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS The Procter and Gamble Company (US) 2006-11-29 EP disclosed
EP-1725642-A1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS The Procter and Gamble Company (US) 2006-11-29 EP disclosed
WO-2005090540-A1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2005-09-29 WO disclosed
WO-2005090541-A1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2005-09-29 WO disclosed
EP-1580201-A1 Aqueous treatment compositions and polymers for use therein National Starch and Chemical Investment Holding Corporation (US) 2005-09-28 EP disclosed
US-20050202995-A1 Methods of treating surfaces using surface-treating compositions containing sulfonated/carboxylated polymers THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 US disclosed
US-20050202996-A1 Surface-treating compositions containing sulfonated/carboxylated polymers THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 US disclosed
US-20050203263-A1 Aqueous treatment compositions and polymers for use therein NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2005-09-15 US disclosed
EP-0590983-B1 Cement dispersion agents TAKEMOTO OIL & FAT CO LTD (JP) 1996-12-18 EP disclosed
EP-0590983-A1 Cement dispersion agents Takemoto Yushi Kabushiki Kaisha (JP) 1994-04-06 EP disclosed