Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201466 | 0.88 | GAA (0.49) | GAACYP3A4CYP2C19ADRB1NOS3 | |
| SCHEMBL16728722 | 0.88 | GAA (0.40) | GAAADRB1NOS3NOS1NOS2 | |
| SCHEMBL20201473 | 0.86 | CYP3A4 (0.43) | GAACYP3A4CYP2C19ADRB1DRD2 | |
| SCHEMBL20201475 | 0.81 | MAPT (0.41) | GAACYP3A4CYP2C19ADRB1TP53 | |
| SCHEMBL15576782 | 0.78 | SMN1; SMN2 (0.38) | GAADRD2NPC1TP53LMNA | |
| SCHEMBL20865195 | 0.77 | TP53 (0.36) | GAATP53LMNASMN1; SMN2MAPT | |
| SCHEMBL20201468 | 0.77 | CYP3A4 (0.44) | GAACYP3A4CYP2C19ADRB1LMNA | |
| SCHEMBL12100620 | 0.77 | GAA (0.39) | GAANPC1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12100575 | 0.76 | DRD2 (0.37) | GAADRD2LMNASMN1; SMN2MAPT | |
| SCHEMBL17754706 | 0.75 | GAA (0.42) | GAAADRB1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180151816-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180151816-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | TEC, EML4, TPR | GAA 4467/4885CYP3A4 2528/4885CYP2C19 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.