Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24777832 | 0.94 | SCN9A (0.49) | SCN9AFFAR4SCN5A | |
| SCHEMBL20376455 | 0.85 | HTR2A (0.38) | SCN9A | |
| SCHEMBL20201737 | 0.85 | CNR2 (0.40) | SCN9AFFAR4 | |
| SCHEMBL20201699 | 0.85 | PDE10A (0.40) | SCN9A | |
| SCHEMBL23909099 | 0.81 | CNR2 (0.38) | SCN9A | |
| SCHEMBL9873759 | 0.81 | FFAR4 (0.44) | SCN9AFFAR4 | |
| SCHEMBL21325088 | 0.80 | SCN9A (0.45) | SCN9AFFAR4 | |
| SCHEMBL20201700 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL16200095 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL23915543 | 0.77 | CNR2 (0.40) | SCN9AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |