Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325274 | 0.78 | CNR2 (0.44) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL22751284 | 0.77 | CYP2C19 (0.34) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL12778269 | 0.76 | SCN10A (0.35) | SMPD3 | |
| SCHEMBL12778265 | 0.69 | MAPT (0.36) | ALDH1A1MAPTKDM4EUSP2HSD17B10 | |
| SCHEMBL25164045 | 0.65 | RXRA (0.40) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL12301395 | 0.63 | L3MBTL1 (0.45) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL13575846 | 0.62 | PIK3CA (0.41) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL2715216 | 0.61 | L3MBTL1 (0.56) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL506299 | 0.61 | CHRNB2 (0.42) | ALDH1A1MAPTKMT2ACYP2C19NPC1 | |
| SCHEMBL18256809 | 0.61 | NOS1 (0.38) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |