Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953582 | 0.79 | CYP3A4 (0.44) | HSD17B10CYP3A4NPSR1MEN1KMT2A | |
| SCHEMBL13716485 | 0.76 | PRKCI (0.46) | HSD17B10CYP3A4NPSR1MEN1KMT2A | |
| SCHEMBL17472001 | 0.75 | HSD17B10 (0.40) | HSD17B10CYP3A4NPSR1MEN1KMT2A | |
| SCHEMBL3735175 | 0.74 | CYP3A4 (0.47) | HSD17B10CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL1087300 | 0.74 | NOS3 (0.37) | HSD17B10NPSR1KMT2ACYP1A2MAPT | |
| SCHEMBL14235957 | 0.74 | IMPDH2 (0.36) | CYP3A4NPSR1IMPDH2 | |
| SCHEMBL24489070 | 0.74 | PRKCI (0.40) | HSD17B10CYP3A4NPSR1HPGDCA12 | |
| SCHEMBL18567675 | 0.73 | HSD17B1 (0.44) | HSD17B10CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL31092533 | 0.73 | GABRA1 (0.41) | HSD17B10CYP3A4NPSR1CYP1A2 | |
| SCHEMBL24672233 | 0.73 | GABRA1 (0.41) | HSD17B10CYP3A4NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180149972-A1 | HIGHLY RESOLVED PHOTOCHEMISTRY BELOW THE DIFFRACTION LIMIT BY MEANS OF SWITCHABLE PHOTO-ENOLIZATION | KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) | 2018-05-31 | — | — | US | disclosed |