SCHEMBL20202525

SCHEMBL20202525

CCCCCCCCCCCCCCCCCC(=O)OC(COC(COCC(O)CO)COCC(O)CO)COC(COCC(O)CO)COCC(O)CO

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.60
MAPK1 P28482 1/20 0.60
LMNA P02545 2/20 0.60
KDM4E B2RXH2 1/20 0.60
DUSP3 P51452 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
ALDH1A1 P00352 1/20 0.57
PRKCA P17252 3/20 0.57
PRKCE Q02156 2/20 0.57
PRKCQ Q04759 2/20 0.57
PRKCD Q05655 2/20 0.57
DGKA P23743 1/20 0.52
SELP P16109 1/20 0.50
USP2 O75604 1/20 0.50
LPAR1 Q92633 2/20 0.48
LPAR3 Q9UBY5 2/20 0.48
ENPP2 Q13822 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202521 0.94 MAPT (0.68) MAPTMAPK1LMNAKDM4EDUSP3
SCHEMBL3453977 0.90 MAPT (0.71) MAPTMAPK1LMNAKDM4EDUSP3
SCHEMBL28225640 0.90 MAPT (0.71) MAPTMAPK1LMNAKDM4EDUSP3
SCHEMBL25635327 0.89 MAPT (0.52) MAPTMAPK1LMNAKDM4EDUSP3
Alcohol SCHEMBL7806293 0.89 MAPT (0.60) MAPTMAPK1LMNAKDM4EDUSP3
SCHEMBL17079319 0.89 LMNA (0.75) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL6114438 0.89 LMNA (0.75) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL14305782 0.88 LMNA (0.73) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL13299394 0.86 LMNA (0.74) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL5420360 0.85 LMNA (0.68) MAPTMAPK1LMNAKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173082-A1 ANTIBACTERIAL PRODUCTS UNIVERSITY OF LINCOLN (GB) 2023-06-08 US disclosed
US-11660350-B2 Antibacterial products UNIVERSITY OF LINCOLN (GB) 2023-05-30 US disclosed
US-20180147290-A1 NEW ANTIBACTERIAL PRODUCTS UNIVERSITY OF LINCOLN (GB) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11660350-B2 Antibacterial products MSN, VAPA, SLC47A2 MAPT 2260/4885MAPK1 3752/4885LMNA 1954/4885
US-20230173082-A1 ANTIBACTERIAL PRODUCTS XIAP, CLSPN, SLC47A2 MAPT 3082/4885MAPK1 4526/4885LMNA 2428/4885
US-20180147290-A1 NEW ANTIBACTERIAL PRODUCTS MSN, VAPA, VAPB MAPT 2802/4885MAPK1 3302/4885LMNA 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.