Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | PRKCA | P17252 | 5/20 | 0.70 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.70 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.70 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453977 | 1.00 | MAPT (0.71) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL20202521 | 0.95 | MAPT (0.68) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL29411373 | 0.91 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| Alcohol SCHEMBL7806293 | 0.90 | MAPT (0.60) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL17079319 | 0.90 | LMNA (0.75) | PRKCAPRKCEPRKCQPRKCDLMNA | |
| SCHEMBL20202525 | 0.90 | MAPT (0.60) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL6114438 | 0.90 | LMNA (0.75) | PRKCAPRKCEPRKCQPRKCDLMNA | |
| SCHEMBL8160400 | 0.89 | PRKCA (0.54) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL27636243 | 0.89 | MAPT (0.59) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL14305782 | 0.89 | LMNA (0.73) | PRKCAPRKCEPRKCQPRKCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947843-A | Prostacyclin compound, its composition and application method | 英斯梅德股份有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-105848479-B | Prostacyclin compounds, compositions and methods of use thereof | 英斯梅德股份有限公司 | 2018-07-13 | — | — | CN | disclosed |