Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.57 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.56 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202521 | 0.94 | MAPT (0.68) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL28225640 | 0.90 | MAPT (0.71) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL3453977 | 0.90 | MAPT (0.71) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL6114438 | 0.89 | LMNA (0.75) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL17079319 | 0.89 | LMNA (0.75) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL20202525 | 0.89 | MAPT (0.60) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL14305782 | 0.88 | LMNA (0.73) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25635327 | 0.87 | MAPT (0.52) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL4567275 | 0.85 | DGKA (0.70) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL6968513 | 0.85 | DGKA (0.70) | MAPTMAPK1LMNAKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079918-A1 | MICROENCAPSULATION AND ELECTROSTATIC PROCESSING METHOD | NASA/Johnson Space Center (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059714-A1 | MICROENCAPSULATION AND ELECTROSTATIC PROCESSING METHOD | NASA/JOHNSON SPACE CENTER (US) | 1999-11-25 | — | — | WO | disclosed |