Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203276 | 0.69 | TRPA1 (0.41) | SMN1; SMN2 | |
| SCHEMBL23718348 | 0.67 | ADORA2A (0.41) | SMN1; SMN2HDAC6KMT2A | |
| SCHEMBL22210245 | 0.60 | TRPA1 (0.38) | — | |
| SCHEMBL19036501 | 0.59 | ALDH1A1 (0.32) | — | |
| SCHEMBL20096657 | 0.56 | YTHDC1 (0.38) | — | |
| SCHEMBL20187462 | 0.55 | KMT2A (0.56) | SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL23892134 | 0.54 | CDK2 (0.47) | — | |
| SCHEMBL20665963 | 0.51 | ALDH1A1 (0.56) | NPC1RAB9AKMT2A | |
| SCHEMBL19526130 | 0.51 | ATAD2 (0.32) | KMT2A | |
| SCHEMBL821227 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096159-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-31 | — | — | WO | disclosed |