Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456758 | 0.88 | IDH1 (0.32) | IDH1IDH2 | |
| SCHEMBL1005117 | 0.86 | IDH1 (0.30) | IDH1IDH2 | |
| SCHEMBL1231052 | 0.82 | IDH1 (0.31) | IDH1IDH2 | |
| SCHEMBL9429082 | 0.81 | KMT2A (0.37) | — | |
| SCHEMBL7458937 | 0.81 | IDH1 (0.33) | IDH1IDH2 | |
| SCHEMBL9428440 | 0.80 | PDE4A (0.32) | — | |
| SCHEMBL7990249 | 0.79 | IDH1 (0.31) | IDH1IDH2 | |
| SCHEMBL8653402 | 0.78 | — | — | |
| SCHEMBL20608531 | 0.78 | GAA (0.33) | IDH1IDH2 | |
| SCHEMBL9428260 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481726-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-07-09 | — | — | US | disclosed |
| US-20110160453-A1 | Process for the preparation of sterically hindered nitroxyl ethers | CIBA CORPORATION | 2011-06-30 | — | — | US | disclosed |
| EP-2035382-B1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | BASF SE (DE) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160453-A1 | Process for the preparation of sterically hindered nitroxyl ethers | PPOX, CBR1, CBR3 | IDH1 661/4885IDH2 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.