SCHEMBL456758

SCHEMBL456758

CCCC(Nc1nc(Cl)nc(NC(CCC)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)n1)C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.32
IDH2 P48735 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDE4A P27815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005117 0.98 IDH1 (0.30) IDH1IDH2
SCHEMBL1231052 0.94 IDH1 (0.31) IDH1IDH2
SCHEMBL9429082 0.92 KMT2A (0.37)
SCHEMBL9428440 0.92 PDE4A (0.32) PDE4A
SCHEMBL8653402 0.90
SCHEMBL9428260 0.89
SCHEMBL599443 0.88 NPR3 (0.32) IDH1
SCHEMBL2020395 0.88 IDH1 (0.30) IDH1IDH2
SCHEMBL9207772 0.87 ADAMTS5 (0.33)
SCHEMBL9210643 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024053584-A1 POLYPROPYLENE-BASED FOAM PARTICLES, POLYPROPYLENE-BASED FOAM MOLDED BODY, AND METHODS FOR PRODUCING SAME 株式会社カネカ 2024-03-14 WO claimed
WO-2023090311-A1 POLYPROPYLENE FOAM PARTICLES AND POLYPROPYLENE FOAM MOLDED BODY, AND METHODS FOR PRODUCING SAME 株式会社カネカ 2023-05-25 WO claimed
US-20230072612-A1 FLAME RETARDANT CHEMICAL COMPOSITIONS NORDTREAT FINLAND OY (FI) 2023-03-09 US claimed
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US claimed
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-08-02 US claimed
EP-3122813-B1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-03-07 EP claimed
EP-3122813-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2017-02-01 EP claimed
EP-2464739-B1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2016-01-13 EP claimed
WO-2015144667-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2015-10-01 WO claimed
US-20150148464-A1 FLAME RETARDANT COMPOSITIONS OF PHOSPHINIC ACID SALTS AND NITROXYL DERIVATIVES BASF SE (DE) 2015-05-28 US claimed
EP-1554336-A1 FLAME RETARDANT COMPOSITIONS Ciba SC Holding AG (CH) 2005-07-20 EP claimed
WO-2005014706-A1 FLAME RETARDANT POLYLACTIC ACID CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 WO claimed
US-20050014948-A1 Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines CIBA SPECIALTY CHEMICALS CORP. 2005-01-20 US claimed
US-20050014871-A1 Flame retardant polylactic acid CIBA SPECIALTY CHEMICALS CORP. 2005-01-20 US claimed
WO-2005005388-A1 HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-01-20 WO claimed
US-20040138351-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed
US-20040116565-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-06-17 US claimed
US-20040097620-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US claimed
US-20040087689-A1 Flame retardant polymeric electrical parts CIBA SPECIALTY CHEMICALS CORP. 2004-05-06 US claimed
WO-2004035671-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS PFAS, PCBP1, DDT IDH1 716/4885IDH2 537/4885GAA 2741/4885
US-20050014948-A1 Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines HAO2, SOD1, PPOX IDH1 350/4885IDH2 431/4885GAA 2096/4885
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT IDH1 259/4885IDH2 244/4885GAA 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.