SCHEMBL20204429

SCHEMBL20204429

Cc1ccc2c(c1)c1ccc(-c3ccc4c5ccccc5n5c6cc(C)ccc6nc5c4c3)cc1n1c3ccccc3nc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.46
ALDH1A1 P00352 8/20 0.46
KDM4E B2RXH2 8/20 0.46
KMT2A Q03164 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 4/20 0.44
POLB P06746 4/20 0.44
HSD17B10 Q99714 4/20 0.44
LMNA P02545 3/20 0.44
TP53 P04637 1/20 0.44
FLT3 P36888 1/20 0.40
GAA P10253 2/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 3/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
TSHR P16473 1/20 0.38
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20204424 0.93 HPGD (0.48) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19849768 0.89 HPGD (0.43) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19849770 0.88 HPGD (0.40) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL13350166 0.87 KDM4E (0.56) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL13350111 0.87 KDM4E (0.56) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL12719969 0.87 KDM4E (0.56) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL26460737 0.86 KDM4E (0.48) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19849793 0.85 HPGD (0.45) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL20156880 0.85 HPGD (0.41) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL12759579 0.85 KDM4E (0.50) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-10-13 US disclosed
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 HPGD 2679/4885ALDH1A1 735/4885KDM4E 2208/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 HPGD 1474/4885ALDH1A1 270/4885KDM4E 2233/4885
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 HPGD 2383/4885ALDH1A1 854/4885KDM4E 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.