SCHEMBL12759579

SCHEMBL12759579

Cc1ccc2nc3c4ccccc4c4ccccc4n3c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
MAPT P10636 4/20 0.50
POLB P06746 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TP53 P04637 1/20 0.50
ALDH1A1 P00352 7/20 0.45
HPGD P15428 6/20 0.45
TSHR P16473 1/20 0.45
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
AHR P35869 2/20 0.43
NR1I2 O75469 1/20 0.43
IKBKB O14920 2/20 0.43
NQO2 P16083 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13350111 0.89 KDM4E (0.56) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL13350117 0.88 KDM4E (0.50) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL12719969 0.86 KDM4E (0.56) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL13350116 0.86 KDM4E (0.56) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL13350166 0.86 KDM4E (0.56) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL20204429 0.85 HPGD (0.46) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL19297269 0.83 MAOA (0.44) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL12145505 0.83 KDM4E (0.45) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL19849768 0.82 HPGD (0.43) KDM4EMAPTPOLBLMNAHSD17B10
SCHEMBL37035230 0.81 KDM4E (0.61) KDM4EMAPTPOLBLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. 2020-12-22 US disclosed
EP-3351523-B1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2020-11-04 EP disclosed
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-10-13 US disclosed
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
EP-3378864-B1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-22 EP disclosed
EP-3321246-B1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP disclosed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US disclosed
EP-3351523-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG Chem, Ltd. (KR) 2018-07-25 EP disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed
WO-2017146474-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE CONTAINING SAME 주식회사 엘지화학 2017-08-31 WO disclosed
WO-2017047993-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME 주식회사 엘지화학 2017-03-23 WO disclosed
WO-2017047992-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2017-03-23 WO disclosed
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-10-29 US disclosed
US-9062084-B2 Method of forming metal complex compound, and organic electroluminescence device UDC Ireland (IE) 2015-06-23 US disclosed
US-20150090968-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-04-02 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 KDM4E 2208/4885MAPT 1231/4885POLB 2676/4885
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 KDM4E 2514/4885MAPT 1946/4885POLB 1381/4885
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device ZFR, PORCN, OR10J3 KDM4E 2514/4885MAPT 1946/4885POLB 1381/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 KDM4E 1258/4885MAPT 754/4885POLB 3877/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 KDM4E 2554/4885MAPT 1166/4885POLB 2412/4885
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, PER2 KDM4E 2554/4885MAPT 1166/4885POLB 2412/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 KDM4E 2233/4885MAPT 1466/4885POLB 2807/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 KDM4E 3335/4885MAPT 1495/4885POLB 3892/4885
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 KDM4E 2233/4885MAPT 1466/4885POLB 2807/4885
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME NR2E3, CRY1, CRY2 KDM4E 3335/4885MAPT 1495/4885POLB 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.