Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206763 | 1.00 | ADRA1A (0.32) | ADRA1AOPRL1HRH2HRH3 | |
| SCHEMBL20376449 | 0.91 | ADRA1A (0.36) | ADRA1AOPRL1 | |
| SCHEMBL20201610 | 0.91 | ADRA1A (0.36) | ADRA1AOPRL1 | |
| SCHEMBL20376448 | 0.83 | ADRA1A (0.34) | ADRA1AOPRL1 | |
| SCHEMBL20201608 | 0.77 | CXCR2 (0.34) | OPRL1 | |
| SCHEMBL20206761 | 0.73 | FEN1 (0.36) | HRH2HRH3 | |
| SCHEMBL20376466 | 0.73 | FEN1 (0.36) | HRH2HRH3 | |
| SCHEMBL22143863 | 0.72 | DRD2 (0.40) | OPRL1HRH2HRH3 | |
| SCHEMBL23987321 | 0.66 | HRH3 (0.35) | HRH2HRH3 | |
| SCHEMBL16729403 | 0.65 | PNMT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |