Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207781 | 1.00 | ADRA1A (0.40) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL20201600 | 0.92 | FABP4 (0.36) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL20204881 | 0.82 | ALOX5AP (0.35) | ADRA1AHTR2CACACBHTR2BHTR2A | |
| SCHEMBL21324913 | 0.82 | ADRA1A (0.38) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL20206774 | 0.82 | ADRA1A (0.38) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL21324931 | 0.82 | ADRA1A (0.38) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL20201595 | 0.79 | ADRA1A (0.35) | ADRA1AFABP4CHUK | |
| SCHEMBL21324914 | 0.77 | FABP4 (0.37) | ADRA1AFABP4HTR2CPDE4DCHUK | |
| SCHEMBL21324930 | 0.77 | FABP4 (0.35) | ADRA1AFABP4ACACBALOX5APFEN1 | |
| SCHEMBL21533824 | 0.77 | FABP4 (0.37) | ADRA1AFABP4HTR2CPDE4DCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |