⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703676 | 0.74 | — | — | |
| SCHEMBL3402808 | 0.68 | — | — | |
| SCHEMBL8880521 | 0.68 | — | — | |
| SCHEMBL8699049 | 0.68 | — | — | |
| SCHEMBL5656550 | 0.67 | CRBN (0.41) | — | |
| SCHEMBL18814744 | 0.66 | CRBN (0.35) | — | |
| SCHEMBL8692840 | 0.65 | CRBN (0.34) | — | |
| SCHEMBL13737078 | 0.64 | CRBN (0.38) | — | |
| SCHEMBL13737400 | 0.64 | TOP2A (0.45) | — | |
| SCHEMBL10653236 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515903-A1 | COMPOUNDS, PREPARATIONS AND USES THEREOF | Peter MacCallum Cancer Institute (AU) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011075784-A1 | COMPOUNDS, PREPARATIONS AND USES THEREOF | PETER MACCALLUM CANCER INSTITUTE (AU) | 2011-06-30 | — | — | WO | disclosed |