Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591613 | 0.77 | MEN1 (0.49) | CRBNMEN1KMT2A | |
| SCHEMBL1980044 | 0.76 | MEN1 (0.43) | CRBNMEN1KMT2A | |
| SCHEMBL10653236 | 0.75 | — | — | |
| SCHEMBL28402591 | 0.75 | — | — | |
| SCHEMBL18814841 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL8026061 | 0.73 | MPO (0.37) | CRBN | |
| SCHEMBL497739 | 0.71 | MAPT (0.39) | CRBNMEN1KMT2A | |
| SCHEMBL3419632 | 0.71 | KMT2A (0.37) | EPHX2MEN1KMT2A | |
| SCHEMBL11580739 | 0.68 | CRBN (0.32) | CRBNMEN1KMT2A | |
| SCHEMBL5955059 | 0.68 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349516-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
| US-20170119721-A1 | COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND A HYDROXYL COMPOUND AND METHODS OF USE THEREOF | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119721-A1 | COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND A HYDROXYL COMPOUND AND METHODS OF USE THEREOF | ALOX5, ALOX15, ALOX12 | CRBN 4688/4885EPHX2 32/4885MEN1 4105/4885 |
| US-20170349516-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | NR1H3, CYP27A1, NR1H2 | CRBN 3099/4885EPHX2 737/4885MEN1 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.