SCHEMBL20205615

SCHEMBL20205615

N/N=C1\CCCc2ccc(F)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.41
PARP10 Q53GL7 1/20 0.41
MAPT P10636 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
NPY5R Q15761 6/20 0.39
KDM1A O60341 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SRD5A1 P18405 1/20 0.36
TYMS P04818 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CTSL P07711 1/20 0.35
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23678197 0.89 PARP1 (0.43) PARP1PARP10MAPTALDH1A1NPY5R
SCHEMBL19754402 0.82 L3MBTL1 (0.53) PARP1PARP10MAPTALDH1A1LMNA
SCHEMBL5469183 0.82 L3MBTL1 (0.53) PARP1PARP10MAPTALDH1A1LMNA
SCHEMBL5469185 0.82 L3MBTL1 (0.53) PARP1PARP10MAPTALDH1A1LMNA
SCHEMBL26622033 0.79 ALDH1A1 (0.43) PARP1PARP10MAPTALDH1A1LMNA
SCHEMBL6340362 0.79 HPGD (0.58) PARP1PARP10MAPTALDH1A1LMNA
SCHEMBL23678473 0.74 CYP11B2 (0.41) SRD5A1
SCHEMBL21098938 0.73 MAPT (0.55) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL1327059 0.73 L3MBTL1 (0.60) MAPTALDH1A1LMNACASP3SENP8
SCHEMBL2068814 0.73 L3MBTL1 (0.60) MAPTALDH1A1LMNACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018097318-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-31 WO disclosed