SCHEMBL1327059

SCHEMBL1327059

NN=C1CCCc2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.60
HPGD P15428 1/20 0.60
G6PC1 P35575 1/20 0.51
CYP2A6 P11509 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
ALDH1A1 P00352 6/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 4/20 0.45
GAA P10253 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
PLA2G1B P04054 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738971 1.00 L3MBTL1 (0.60) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL2068814 1.00 L3MBTL1 (0.60) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL30460772 1.00 L3MBTL1 (0.60) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL20457143 0.96 L3MBTL1 (0.66) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL20457146 0.87 SMN1; SMN2 (0.51) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL11606504 0.87 SMN1; SMN2 (0.51) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL11606503 0.87 SMN1; SMN2 (0.51) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL10805608 0.83 L3MBTL1 (0.64) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL16489779 0.79 L3MBTL1 (0.60) L3MBTL1HPGDG6PC1CYP2A6MAOA
SCHEMBL12786315 0.79 L3MBTL1 (0.60) L3MBTL1HPGDG6PC1CYP2A6MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089023-B1 STABILIZER SYSTEMS USEFUL IN LUBRICATING OILS AND METHOD FOR STABILIZING LUBRICATING OILS UNIROYAL, INC. (US) 1987-10-07 EP claimed
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-01-18 US disclosed
EP-3544973-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL CO (JP) 2021-07-28 EP disclosed
WO-2018097318-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-31 WO disclosed
EP-1565452-B1 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS NOVARTIS INT PHARM LTD (BM) 2012-04-04 EP disclosed
US-20110281837-A1 3-SUBSTITUTED-6-ARYL PYRIDINES HUTCHINSON ALAN J (US) 2011-11-17 US disclosed
US-7863454-B2 3-substituted-6-aryl pyridines NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2011-01-04 US disclosed
US-20090176980-A1 3-Substituted-6-Aryl Pyridines NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2009-07-09 US disclosed
US-7342115-B2 Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology NEUROGEN CORPORATION (US) 2008-03-11 US disclosed
EP-1565452-A2 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS NEUROGEN CORPORATION (US) 2005-08-24 EP disclosed
US-20040158067-A1 3-substituted-6-aryl pyridines NEUROGEN CORPORATION 2004-08-12 US disclosed
WO-2004043925-A2 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS NEUROGEN CORPORATION (US) 2004-05-27 WO disclosed
EP-0089023-B1 STABILIZER SYSTEMS USEFUL IN LUBRICATING OILS AND METHOD FOR STABILIZING LUBRICATING OILS UNIROYAL, INC. (US) 1987-10-07 EP disclosed
US-4469609-A OXIDATION RESISTANCE UNIROYAL, INC. (US) 1984-09-04 US disclosed
EP-0089023-A1 Stabilizer systems useful in lubricating oils and method for stabilizing lubricating oils UNIROYAL, INC. (US) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110281837-A1 3-SUBSTITUTED-6-ARYL PYRIDINES C3AR1, C5AR1, C5AR2 L3MBTL1 3202/4885HPGD 2471/4885G6PC1 2272/4885
US-20090176980-A1 3-Substituted-6-Aryl Pyridines C3AR1, C5AR1, C5AR2 L3MBTL1 3202/4885HPGD 2471/4885G6PC1 2272/4885
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents CYC1, MT-CO1, CTRL L3MBTL1 68/4885HPGD 4542/4885G6PC1 566/4885
US-20040158067-A1 3-substituted-6-aryl pyridines C3AR1, C5AR1, C5AR2 L3MBTL1 3716/4885HPGD 2083/4885G6PC1 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.