SCHEMBL20206196

SCHEMBL20206196

CC(=O)NCC(=O)N[C@H]1CCC(=O)NCC[C@@H](C(=O)NCC(=O)O)NC(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 2/20 0.38
▸ TUBB P07437 2/20 0.38
▸ TUBA3C P0DPH7 2/20 0.38
▸ TUBA1B P68363 2/20 0.38
▸ TUBA4A P68366 2/20 0.38
▸ TUBB4B P68371 2/20 0.38
▸ TUBB3 Q13509 2/20 0.38
▸ TUBB2A Q13885 2/20 0.38
▸ TUBB8 Q3ZCM7 2/20 0.38
▸ TUBA3E Q6PEY2 2/20 0.38
▸ TUBA1A Q71U36 2/20 0.38
▸ TUBA1C Q9BQE3 2/20 0.38
▸ TUBB6 Q9BUF5 2/20 0.38
▸ TUBB2B Q9BVA1 2/20 0.38
▸ TUBB1 Q9H4B7 2/20 0.38
▸ TSLP Q969D9 2/20 0.37
▸ OPRM1 P35372 4/20 0.37
▸ OPRD1 P41143 4/20 0.37
▸ OPRK1 P41145 2/20 0.37
▸ MC4R P32245 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20206173 0.95 TSLP (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22606172 0.94 TSLP (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20362936 0.92 TSLP (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20363003 0.91 MC4R (0.40) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20206167 0.91 FCGRT (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20206327 0.90 MC4R (0.39) TSLPOPRM1OPRD1OPRK1MC4R
SCHEMBL22606167 0.89 TSLP (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22606361 0.89 MC4R (0.39) TSLPOPRM1OPRD1OPRK1MC4R
SCHEMBL24990007 0.89 MC4R (0.37) TSLPOPRM1OPRD1OPRK1MC4R
SCHEMBL20362935 0.88 TSLP (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine PALATIN TECHNOLOGIES, INC. (US) 2020-07-14 — — US disclosed
US-10017539-B2 Melanocortin-1 receptor-specific cyclic hexapeptides PALATIN TECHNOLOGIES, INC. (US) 2018-07-10 — — US disclosed
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine PALATIN TECHNOLOGIES INC (US) 2018-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711039-B2 Melanocortin receptor-specific peptide with C-terminal naphthylalanine MC1R, MC3R, MC4R TUBB4A 3433/4885TUBB 3174/4885TUBA3C 3113/4885
US-10017539-B2 Melanocortin-1 receptor-specific cyclic hexapeptides MC1R, MC3R, MC5R TUBB4A 4844/4885TUBB 4816/4885TUBA3C 4687/4885
US-20180148478-A1 Melanocortin Receptor-Specific Peptide with C-Terminal Naphthylalanine MC1R, MC3R, MC4R TUBB4A 3433/4885TUBB 3174/4885TUBA3C 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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